Planning projects across the R&D boundary to balance time, cost and risk

Tessella’s portfolio management support experience with Portmanto focuses on better estimation of risk, supporting users to drill down into the various interacting causes of failure and to represent the overall uncertainty in a project.
We can also help companies to analyse, and train project managers and teams on, the most effective approach to derisking each project:

• whether to follow eIND or other ‘early derisking’ approaches
• how much to rely on biomarkers that may not yet be fully validated
• where to apply adaptive designs that help speed lower cost go/no-go decisions
• how far to undertake work at risk ahead of a stage gate
• how best to work with partly uncertain information that informs these strategic decisions, such as market value forecasts and discovery assessments of safety profile.

Key parts of this service are specific analysis of case studies, provision of a robust analysis that shows the sensitivity to assumptions, and creation of bespoke planning support modules that take on board the client’s existing portfolio and planning experience.