In this free webinar Tom Parke discusses key questions about the use of quantitative decision making in drug development through simulation. Model based drug development produces estimates of the likely response to a drug, how should this be used to design a trial? The environment for drug development is becoming more complex, with issues such as sub-population analysis, safety, comparative effectiveness and using drugs in combination is more and more commonplace. How can development teams decide what to explore in the next trial and how can they decide whether to continue or abandon development?  Simulating all the remaining phases of development up to registration and comparing the performance of different strategies is one approach. But is it too complex? Is there too much uncertainty? Will it take too long to run? Could the results be trusted?

• Data overload in the digital oilfield – The quantity and range of real time sensor data in the digital oilfield provides opportunities to improve operations and production, but gaining this insight requires a planned approach to data processing.
• Client Story – CEDA and Tessella collaboration brings Earth observation data to life
• Client Story – WWARN software tools provide global insight into the emergence of antimalarial resistance

http://www.tessella.com/wp-content/uploads/publications/tessellanews74_%23_%2322.pdf

2012 sees a new organisation at Tessella aimed at maximizing the value of its technology and consulting services to clients through greater business focus and geographical alignment.

Board member Jon Tilbury takes on global responsibility for Tessella’s archiving business. He will continue to develop Tessella’s world class archiving software SDB, already in use at many national archives and libraries, as well directing the development of a new “on demand” service based on the same technology.

The creation of four sector Sales Directors reporting to Director Alan Gaby will enable Tessella to develop the services needed by clients to support their industry specific business objectives. Grant Stephen, CEO Tessella Inc. and board member of parent Tessella plc, will work alongside the sector directors in the U.S. to ensure that they address the global needs of Tessella’s clients.

Kevin Gell, Chairman, commented, “Alan, Grant and Jon are hugely experienced executives with long and successful track records of leading world class technology and consulting services. Our growth plans are ambitious but we couldn’t have better leaders to take on the challenge. This is an exciting time for Tessella.”

Play webinar

Oxford, UK | 15th December 2011. Tessella, the international provider of science powered technology and consulting services, is proud to be hosting a free online webinar for all life sciences professionals interested in deepening their understanding of Adaptive Clinical Trials.

Clinical trials that employ frequent adaptation offer great opportunity but pose specific challenges. In this free webinar adaptive trial veterans; Tom Parke (Head of Clinical Trial Solutions, Tessella ) and Martin Kimber (Project Manager, Adaptive Clinical Trials, Tessella) will share their experience gained on over 30 adaptive trials. The webinar will discuss: what these trials are, why people run them, how they are designed, how the logistics to run them are put together, what it’s like to run one as well as observed benefits both expected and unexpected.

The “Running Adaptive Clinical Trials; Myth and Reality webinar” will take place on Thursday December 15th 2011, 3:00 PM (GMT) Greenwich Mean Time: Dublin, Edinburgh, Lisbon, and London. To register online for the event visit: https://tessella.adobeconnect.com/_a970567468/runningadaptivetrialsevent/event/event_info.html

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Notes to the Editor

About Tessella
Founded in 1980, Tessella is the international provider of science powered technology and consulting services. World leading organizations choose our unique blend of science, engineering and sector expertise to deliver innovative and cost-effective solutions to complex real-world commercial and technical challenges. Our people are high achievers from leading universities and are passionate about delivering value to clients.

For further information visit our dedicated microsite on http://www.smarterclinicaltrials.com

Media Contact

Tessella
Christina Tealdi | Public and Analyst Relations Executive
Phone: +44 (0) 1235 555511 | Mobile: + 44 (0) 779 9346453 | christina.tealdi@tessella.com

Each year Tessella sponsors prizes within the physics departments of several top universities. A prize is awarded, by each university, to the student who makes the most effective use of software in their final year physics projects.

This year, at UCL, Dino Osmanovic from the Department of Physics and Astronomy received the Tessella Software prize from Colin Maule, Technical Manager at Tessella.

Dino Osmanovic  investigated polymers that control how molecules can enter a cell’s nucleus through pores.  He used Monte Carlo and free energy density functional techniques, coded in Mathematica and C, to calculate the pore state phase diagram and to show how the weakened attractions between blocking polymers can open up pores in the nucleus’ envelope. For his PhD thesis,

Dino Osmanovic will extend this research to investigate how viruses can trick pores to open up and thereby enter the nucleus.

Also available to download on YouTube